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Description: |
8 pages : tables ; 26 cm. |
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With Note: |
With: Identification of MS-222 residues in selected fish tissues by thin layer chromatography / by John L. Allen, Charles W. Luhning, and Paul D. Harman (No. 41) -- Effect of MS-222 on electrolyte and water content in the brain of rainbow trout / by Wayne A. Willford (No. 43). |
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Bibliography Note: |
Includes bibliographical references (pages 7-8). |
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Summary, Etc. Note: |
Abstract: Eleven species of freshwater fishers were rapidly anesthetized in solutions of MS-222 containing from 100 to 1,000 milligrams of MS-222 per liter. MS-222 concentrations in blood and brain after 1 minute of exposure indicate that MS-222 rapidly diffuses across the gill and passes the blood-brain barrier. Evidence of metabolism of the drug was seen in the presence of acetylated MS-222 in the blood of all species studied. The concentration of free MS-222 in the brain increased with depth of anesthesia to loss of reflex and then either increased or declined slightly as the fish approached medullary collapse. |