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Description: |
vi, 134, A2 pages : illustrations (some color) ; 25 cm |
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Bibliography Note: |
Includes bibliographical references and index. |
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Summary, Etc. Note: |
Prions are infectious, self-propagating proteinaceous agents that cause fatal neurodegenerative diseases, including Creutzfeldt-Jakob Disease (CJD) in humans, scrapie in sheep and goats, and bovine spongiform encephalopathy (BSE) in cattle. In recent years great strides have been made in our understanding of the mechanism of prion propagations and neurotoxicity, however much remains to be discovered. In this book, renowned prion experts review the most recent advances to provide an overview of the field. |
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Contents Note: |
Contents: Machine generated contents note: 1. Introduction / Akikazu Sakudo -- 2. Prion Protein and the Family Members, Doppel and Shadoo / Akikazu Sakudo -- 3. Function of Cellular Prion Protein / Akikazu Sakudo -- 4. Effect of Microglial Inflammation in Prion Disease / Takashi Onodera -- 5. Molecular Mechanisms of Prion Diseases / Markus Glatzel -- 6. Inactivation of Prion and Endotoxins / Gerald McDonnell -- 7. Clinical Aspects of Human Prion Diseases / Richard Knight -- 8. Immunological Strategies for the Prevention and Treatment of Prion Diseases / Suehiro Sakaguchi -- 9. Bovine Spongiform Encephalopathy and Scrapie / Takashi Yokoyama -- 10. Chronic Wasting Disease and Other Animal Prion Diseases / Akikazu Sakudo -- 11. Future Prospects / Katsuaki Sugiura. |